Staging of brain pathology related to sporadic Parkinson’s disease

@article{Braak2003StagingOB,
  title={Staging of brain pathology related to sporadic Parkinson’s disease},
  author={Heiko Braak and Kelly Del Tredici and Udo R{\"u}b and Rob A. I. Vos and Ernst N. H. Jansen Steur and E. van Braak},
  journal={Neurobiology of Aging},
  year={2003},
  volume={24},
  pages={197-211}
}
Sporadic Parkinson's disease involves multiple neuronal systems and results from changes developing in a few susceptible types of nerve cells. Essential for neuropathological diagnosis are alpha-synuclein-immunopositive Lewy neurites and Lewy bodies. The pathological process targets specific induction sites: lesions initially occur in the dorsal motor nucleus of the glossopharyngeal and vagal nerves and anterior olfactory nucleus. Thereafter, less vulnerable nuclear grays and cortical areas… Expand

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