Stages of embryonic development of the zebrafish

  title={Stages of embryonic development of the zebrafish},
  author={Charles B. Kimmel and William W. Ballard and S R Kimmel and Bonnie Ullmann and Thomas Friedrich Schilling},
  journal={Developmental Dynamics},
We describe a series of stages for development of the embryo of the zebrafish, Danio (Brachydanio) rerio. [] Key Result The stages, and their names, are based on morphological features, generally readily identified by examination of the live embryo with the dissecting stereomicroscope.

Cell cycles and development in the embryonic zebrafish.

  • D. Kane
  • Biology
    Methods in cell biology
  • 1999

The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development.

A highly dynamic but also highly stereotypic pattern of vascular connections is found, with different sets of primitive embryonic vessels severing connections and rewiring in new configurations according to a reproducible plan.

Working with zebrafish at postembryonic stages.

Flat Mount Preparation for Observation and Analysis of Zebrafish Embryo Specimens Stained by Whole Mount In situ Hybridization

The WISH protocol is provided for one or two-color detection of gene expression in the zebrafish embryo, and how the flat mounting procedure can be performed on this example of a stained fixed specimen is demonstrated.

Formation of the vertebrate embryo: Moving beyond the Spemann organizer.

Apoptosis in the developing zebrafish embryo.

This work has used the in situ terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) to describe the temporal and spatial distribution of apoptotic cells during normal development of the zebrafish embryo from 12 to 96 h postfertilization.



Mitotic domains in the early embryo of the zebrafish

It is shown that functionally distinct subsets of cells that arise during this period of midblastula transition in the zebrafish have reproducibly different mitotic cycle lengths.

Patterning the brain of the zebrafish embryo.

  • C. Kimmel
  • Biology
    Annual review of neuroscience
  • 1993
This review discusses how brain morphogenesis is related to the arrange­ ments of the earliest neurons and their axons in a simple vertebrate, the zebrafish Brachydanio rerio. Descriptive work

A fate map of the epiblast of the early chick embryo.

The apparently independent behaviour of certain cell populations suggests that at least some presumptive cell types within the epiblast are already specified at preprimitive streak stages.

The fates of the blastomeres of the 16-cell zebrafish embryo.

A fate map for the 16-cell-stage blastomeres of the zebrafish embryo Brachydanio rerio is constructed by assigning probabilities for the contribution of each blastomere to each of 31 tissues in the 26-hour embryo.

Cell movements and cell fate during zebrafish gastrulation.

  • R. Ho
  • Biology
    Development (Cambridge, England). Supplement
  • 1992
These experiments support the hypothesis that cell fate in the vertebrate embryo is determined by cell position, and single cell transplantation experiments designed to test for the irreversible restriction or 'commitment' of embryonic blastomeres in the zebrafish embryo are described.

A mutation that changes cell movement and cell fate in the zebrafish embryo

A zygotic lethal mutation in the zebrafish, Brachydanio rerio, that also changes how particular embryonic cells develop is described, and in mutants these cells may enter a new body region, the tail, and there may express a new fate appropriate for the changed position.

A fate map for the first cleavages of the zebrafish

The use of fluorescent dyes on very-high-molecular-mass carriers to trace a fate map from the first three cleavages of the zebrafish embryo to the three principal adult body axes.

Dynamics of pigment pattern formation in the zebrafish, Brachydanio rerio. I. Establishment and regulation of the lateral line melanophore stripe during the first eight days of development

It is proposed that some “exclusion principle” operates in this embryonic cell population, controlling the positions along the stripe where second wave melanophores can appear, and that this principle regulates and perfects the stripe.

Origin and organization of the zebrafish fate map.

We have analyzed lineages of cells labeled by intracellular injection of tracer dye during early zebrafish development to learn when cells become allocated to particular fates during development, and

Fate map for the 32-cell stage of Xenopus laevis.

A complete fate map has been produced for the 32-cell stage of Xenopus laevis, using donor embryos uniformly labelled with the lineage label fluorescein-dextran-amine to show the fate of each blastomere in terms of tissue types, composition and location of each prospective region on the embryo.