Stage-dependent alterations of the serum cytokine pattern in colorectal carcinoma

  title={Stage-dependent alterations of the serum cytokine pattern in colorectal carcinoma},
  author={Tiina Kantola and Kai Hans Klintrup and Juha P V{\"a}yrynen and Juha O. Vornanen and Risto Seppo Bloigu and Toni Karhu and Karl-Heinz Herzig and Juha P N{\"a}p{\"a}nkangas and Jyrki Tapani M{\"a}kel{\"a} and Tuomo Juhani Karttunen and Anne Tuomisto and Markus J. M{\"a}kinen},
  booktitle={British Journal of Cancer},
Background:Inflammation contributes to the pathogenesis of colorectal cancer (CRC), and cytokine levels are altered during colorectal carcinogenesis.Methods:The serum levels of 13 cytokines and their relation to clinical and pathological parameters, and systemic inflammatory response (mGPS, CRP and neutrophil–lymphocyte ratio), were analysed from a prospective series of 148 CRC patients and 86 healthy age- and sex-matched controls.Results:CRC patients had higher serum platelet-derived growth… CONTINUE READING
65 Citations
52 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 65 extracted citations


Publications referenced by this paper.
Showing 1-10 of 52 references

Elevated levels of circulating IL-7 and IL-15 in patients with early stage prostate cancer

  • C Mengus, C Le Magnen, +7 authors S Wyler
  • J Transl Med
  • 2011
1 Excerpt

Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

  • JC Mathers, DT Bishop
  • Lancet
  • 2011

Blood-based biomarker profiles for detecting lung cancer

  • G Lee, JM Lee, +6 authors SM Dubinett
  • J Thorac Oncol
  • 2010
1 Excerpt

Carcinoma of the colon and rectum

  • Hamilton, FT Bosman, +6 authors LH Sobin
  • Pathology and genetics of tumours of the…
  • 2010
1 Excerpt

Similar Papers

Loading similar papers…