Stable variants of sperm aneuploidy among healthy men show associations between germinal and somatic aneuploidy.

@article{Rube2002StableVO,
  title={Stable variants of sperm aneuploidy among healthy men show associations between germinal and somatic aneuploidy.},
  author={Jiř{\'i} Rube{\vs} and Miluse Vozdova and Wendie Anne Robbins and Olga Řez{\'a}{\vc}ov{\'a} and Sally D. Perreault and Andrew J. Wyrobek},
  journal={American journal of human genetics},
  year={2002},
  volume={70 6},
  pages={1507-19}
}
Repeated semen specimens from healthy men were analyzed by sperm fluorescence in situ hybridization (FISH), to identify men who consistently produced elevated frequencies of aneuploid sperm and to determine whether men who were identified as stable variants of sperm aneuploidy also exhibited higher frequencies of aneuploidy in their peripheral blood lymphocytes. Seven semen specimens were provided by each of 15 men over a 2-year period and were evaluated by the X-Y-8 multicolor sperm FISH… CONTINUE READING
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