Stable surface coating of silicone elastomer with phosphorylcholine and organosilane copolymer with cross-linking for repelling proteins.

Abstract

Poly(dimethylsiloxane) (PDMS)-based polymers are widely used in blood-contacting medical devices. However, the hydrophobic property causes adsorption of plasma proteins and activates blood clotting. There are several techniques for PDMS surface modification. However, the efficacy is limited to short duration due to the low glass transition temperature of… (More)
DOI: 10.1016/j.colsurfb.2015.07.040

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