Stable overexpression of human metallothionein-IIA in a heart-derived cell line confers oxidative protection.

Abstract

Metallothionein (MT) is a metal binding protein and cardioprotective. In order to understand the molecular mechanisms underlying the role of MT in the heart, in the current study we established a stable MT-IIA over-expressing cardiac cell line, and evaluated its anti-oxidative property. Rat heart-derived H9c2 cell line was stably transfected with a vector… (More)
DOI: 10.1016/j.toxlet.2009.03.007

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