Stable metal-organic frameworks containing single-molecule traps for enzyme encapsulation.

@article{Feng2015StableMF,
  title={Stable metal-organic frameworks containing single-molecule traps for enzyme encapsulation.},
  author={Dawei Feng and Tian-Fu Liu and Jie Su and Mathieu Bosch and Zhangwen Wei and Wei Wan and Daqiang Yuan and Ying-Pin Chen and Xuan Wang and Kecheng Wang and Xizhen Lian and Zhi-Yuan Gu and Jihye Park and Xiaodong Zou and Hong-Cai Zhou},
  journal={Nature communications},
  year={2015},
  volume={6},
  pages={5979}
}
Enzymatic catalytic processes possess great potential in chemical manufacturing, including pharmaceuticals, fuel production and food processing. However, the engineering of enzymes is severely hampered due to their low operational stability and difficulty of reuse. Here, we develop a series of stable metal-organic frameworks with rationally designed ultra-large mesoporous cages as single-molecule traps (SMTs) for enzyme encapsulation. With a high concentration of mesoporous cages as SMTs, PCN… CONTINUE READING
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