Stable isotope metabolic labeling suggests differential turnover of the DPYSL protein family.

@article{Turck2016StableIM,
  title={Stable isotope metabolic labeling suggests differential turnover of the DPYSL protein family.},
  author={Christoph Wilhelm Turck and Christian Webhofer and Markus Nussbaumer and Larysa Teplytska and Alon Chen and Giuseppina Maccarrone and Michaela D. Filiou},
  journal={Proteomics. Clinical applications},
  year={2016},
  volume={10 12},
  pages={
          1269-1272
        }
}
PURPOSE In this work, we discuss how in vivo 15 N metabolic labeling in combination with MS simultaneously provides information on protein expression and protein turnover. EXPERIMENTAL DESIGN We metabolically labeled mice with the stable nitrogen isotope 15 N using a 15 N-enriched diet and analyzed unlabeled (14 N) versus 15 N-labeled brain tissue with LC… CONTINUE READING