Stable expression of intracellular Notch suppresses v-Src-induced transformation in avian neural cells

@article{Matos2007StableEO,
  title={Stable expression of intracellular Notch suppresses v-Src-induced transformation in avian neural cells},
  author={St{\'e}phanie Mat{\'e}os and Samira Amarir and Danielle Laugier and Maria Marx and Georges Calothy},
  journal={Oncogene},
  year={2007},
  volume={26},
  pages={3338-3351}
}
Understanding how disruption of differentiation contributes to the cancer cell phenotype is required to identify alterations essential for malignant transformation and provide experimental basis for their correction. We investigated whether primary quail neuroretina cells, transformed by a conditional v-Src mutant (QNR/v-srcts), could revert to a normal… CONTINUE READING