Stable association between strains of Mycobacterium tuberculosis and their human host populations.

@article{Hirsh2004StableAB,
  title={Stable association between strains of Mycobacterium tuberculosis and their human host populations.},
  author={A. E. Hirsh and Anthony George Tsolaki and Kathryn Deriemer and Marcus W. Feldman and Peter M. Small},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 14},
  pages={
          4871-6
        }
}
Mycobacterium tuberculosis is an important human pathogen in virtually every part of the world. Here we investigate whether distinct strains of M. tuberculosis infect different human populations and whether associations between host and pathogen populations are stable despite global traffic and the convergence of diverse strains of the pathogen in cosmopolitan urban centers. The recent global movement and transmission history of 100 M. tuberculosis isolates was inferred from a molecular… CONTINUE READING

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