Stable and dynamic axes of polarity use distinct formin isoforms in budding yeast.

@article{Pruyne2004StableAD,
  title={Stable and dynamic axes of polarity use distinct formin isoforms in budding yeast.},
  author={David Pruyne and Lina Gao and Erfei Bi and Anthony Bretscher},
  journal={Molecular biology of the cell},
  year={2004},
  volume={15 11},
  pages={
          4971-89
        }
}
Bud growth in yeast is guided by myosin-driven delivery of secretory vesicles from the mother cell to the bud. We find transport occurs along two sets of actin cables assembled by two formin isoforms. The Bnr1p formin assembles cables that radiate from the bud neck into the mother, providing a stable mother-bud axis. These cables also depend on septins at the neck and are required for efficient transport from the mother to the bud. The Bni1p formin assembles cables that line the bud cortex and… CONTINUE READING
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