Stable RNA nanoparticles as potential new generation drugs for cancer therapy.


Human genome sequencing revealed that only ~1.5% of the DNA sequence coded for proteins. More and more evidence has uncovered that a substantial part of the 98.5% so-called "junk" DNAs actually code for noncoding RNAs. Two milestones, chemical drugs and protein drugs, have already appeared in the history of drug development, and it is expected that the… (More)
DOI: 10.1016/j.addr.2013.11.006