Stable Polycomb-dependent transgenerational inheritance of chromatin states in Drosophila

  title={Stable Polycomb-dependent transgenerational inheritance of chromatin states in Drosophila},
  author={Filippo Ciabrelli and Federico Comoglio and S Fellous and Boyan Bonev and Maria Ninova and Quentin Szabo and Anne Xuereb and Christophe Klopp and A. A. Aravin and Renato Paro and Fr{\'e}d{\'e}ric Bantignies and Giacomo Cavalli},
  booktitle={Nature Genetics},
Transgenerational epigenetic inheritance (TEI) describes the transmission of alternative functional states through multiple generations in the presence of the same genomic DNA sequence. Very little is known about the principles and the molecular mechanisms governing this type of inheritance. Here, by transiently enhancing 3D chromatin interactions, we established stable and isogenic Drosophila epilines that carry alternative epialleles, as defined by differential levels of Polycomb-dependent… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 160 times over the past 90 days. VIEW TWEETS
9 Citations
53 References
Similar Papers


Publications citing this paper.
Showing 1-9 of 9 extracted citations


Publications referenced by this paper.
Showing 1-10 of 53 references

Functional Dissection of the Blocking and Bypass Activities of the Fab-8 Boundary in the Drosophila Bithorax Complex

  • O Kyrchanova
  • PLoS Genet. 2016;
  • 2016

Similar Papers

Loading similar papers…