Stable COPD: predicting benefit from high-dose inhaled corticosteroid treatment.

@article{Leigh2006StableCP,
  title={Stable COPD: predicting benefit from high-dose inhaled corticosteroid treatment.},
  author={Richard Leigh and Marcia Margaret Menezes Pizzichini and Mr Mark Morris and François Maltais and Frederick E. Hargreave and Emilio Pizzichini},
  journal={The European respiratory journal},
  year={2006},
  volume={27 5},
  pages={964-71}
}
The role of inhaled corticosteroids in the management of chronic obstructive pulmonary disease (COPD) remains controversial. The purpose of this study was to evaluate whether sputum eosinophilia (defined as eosinophils > or = 3%) predicts clinical benefit from inhaled corticosteroid treatment in patients with smoking-related clinically stable moderate-to-severe COPD. Forty consecutive patients with effort dyspnoea (mean age 67 yrs; 52 pack-yr smoking history; post-bronchodilator forced… CONTINUE READING

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