Stabilizers and destabilizers controlling cell cycle oscillators.

@article{Guardavaccaro2006StabilizersAD,
  title={Stabilizers and destabilizers controlling cell cycle oscillators.},
  author={Daniele Guardavaccaro and Michele Pagano},
  journal={Molecular cell},
  year={2006},
  volume={22 1},
  pages={1-4}
}
Various destabilizing factors of the ubiquitin system contribute to the synchrony and unidirectionality of the cell cycle clock by finely tuning the activity of various CDKs. The recent findings of hierarchical and connected waves of cyclin stabilizers highlight the complexity of this network. 

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