• Corpus ID: 43426764

Stabilized NADH improves the physical and mental performance in highly conditioned athletes

  title={Stabilized NADH improves the physical and mental performance in highly conditioned athletes},
  author={Georg Dr Birkmayer and Karl Nadlinger},
In 1995 a study was conducted among competitive-level cyclists and long distance runners taking ENADA/NADH. A significant range of performance improvements was recorded such as increased oxygen capacity, decreased reaction time and greater mental acuity. Based on these results a double blind, placebo-controlled cross-over study was organized at the Department of Sports Medicine of the University Clinic in Freiburg, Germany with the new sublingual NADH formulation (ENADAlert) with highly… 

Figures from this paper

Effects of nicotinamide adenine dinucleotide hydride on physical and mental performance

The results indicated that [Vdot]O2max, maximal anaerobic running time, and the ability to concentrate were similar in the NADH and placebo conditions, and there were no differences in blood lactate, creatine kinase, reaction time or feelings of fatigue between the treatments.



Skeletal muscle metabolism in the chronic fatigue syndrome. In vivo assessment by 31P nuclear magnetic resonance spectroscopy.

Patients with CFS and normal control subjects have similar skeletal muscle metabolic patterns during dynamic exercise and reach similar clinical and metabolic end points, however, CFS patients reach exhaustion much more rapidly than normal subjects, at which point they also have relatively reduced intracellular concentrations of ATP.

Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome.

Nicotinamide adenine dinucleotide (NADH)--a new therapeutic approach to Parkinson's disease. Comparison of oral and parenteral application.

The orally applied form of NADH yielded an overall improvement in the disability which was comparable to that of the parenterally applied form, and younger patients and patients with a shorter duration of disease have a better chance to gain a marked improvement.

NADH supplementation decreases pinacidil‐primed IK(ATP) in ventricular cardiomyocytes by increasing intracellular ATP

Data show that supplementation of guinea‐pig ventricular cardiomyocytes with NADH results in a decreased activation of IK(ATP) by pinacidil compared to control myocytes, indicating a higher subsarcolemmal ATP concentration.

Energy Conversion: Mitochondria and Chloroplasts

Comparisons of DNA sequences indicate that the energy-converting organelles in present-day eukaryotes originated from prokaryotic cells that were endocytosed during the evolution of eUKaryotes, explaining why mitochondria and chloroplasts contain their own DNA, which still encodes a subset of their proteins.

Influence of Reduced Nicotinamide Adenine Dinucleotide on the Production of Interleukin-6 by Peripheral Human Blood Leukocytes

It is concluded that NADH possesses cytokine-modulating effects on peripheral blood cells, and significantly stimulated the dose-dependent release of IL-6 in PBLs from the 18 healthy donors.

Oxidative phosphorylation.

Examination of the Bioavailability of Reduced Nicotinamide Adenine Dinucleotide (NADH) in the CNS of the Anaesthetized Rat by Laser-Induced Fluorescence Spectroscopy

  • Biological Chemistry,
  • 2001

“ Enzyme - based Assay fir Determining Effects of Exogenous and Endogenous Factors of Cellular Energy Production ”

  • Patentschrift , U . S . Patentnr