Stabilization of flagellar filaments by HAP2 capping

@article{Diszeghy2004StabilizationOF,
  title={Stabilization of flagellar filaments by HAP2 capping},
  author={Z. Di{\'o}szeghy and P. Z{\'a}vodszky and K. Namba and F. Vonderviszt},
  journal={FEBS Letters},
  year={2004},
  volume={568}
}
  • Z. Diószeghy, P. Závodszky, +1 author F. Vonderviszt
  • Published 2004
  • Medicine, Chemistry
  • FEBS Letters
  • In vivo growth of bacterial flagellar filaments by self‐assembly of flagellin is promoted by a capping structure composed of a pentameric assembly of hook associated protein 2 (HAP2). Isolated native filaments with intact HAP2 cap exhibited higher melting temperature (ΔT m=4 °C) and significantly increased resistance against heat‐induced depolymerization than non‐capped ones. Reconstituted filaments were also stabilized by HAP2 binding, but the obtained filament–HAP2 complexes were less stable… CONTINUE READING
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