Stabilization by host cell components and Mg2+ of the neutralization epitopes of poliovirus.

Abstract

When type 1 poliovirions were extracted from infected HeLa cells and heated at 56 degrees C in the presence of 1 mM-Mg2+, RNA-free, pluri-antigenic particles were formed. These particles possessed neutralization epitopes as well as epitopes associated with H antigen and with the isolated capsid protein VP3. The heating caused the formation of exclusively H… (More)

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Cite this paper

@article{Rombaut1985StabilizationBH, title={Stabilization by host cell components and Mg2+ of the neutralization epitopes of poliovirus.}, author={Bart Rombaut and Raf Vrijsen and A. Boey{\'e}}, journal={The Journal of general virology}, year={1985}, volume={66 ( Pt 2)}, pages={303-7} }