Stability profiles of nepenthesin in urea and guanidine hydrochloride: comparison with porcine pepsin A.

@article{Kubota2010StabilityPO,
  title={Stability profiles of nepenthesin in urea and guanidine hydrochloride: comparison with porcine pepsin A.},
  author={Keiko Kubota and Yuya Metoki and Senarath B P Athauda and Chiaki Shibata and Kenji Takahashi},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2010},
  volume={74 11},
  pages={2323-6}
}
Nepenthesin, an aspartic endopeptidase from the pitcher fluid of Nepenthes, was found to be markedly less stable than porcine pepsin A when treated with urea or guanidine hydrochloride. This is in sharp contrast with its remarkably high pH/temperature stability as compared with porcine pepsin A. No protein with such a stability profile has been reported to… CONTINUE READING