Stability of viability and immunizing potency of lyophilized, modified equine arteritis live-virus vaccine.

@article{Harry1981StabilityOV,
  title={Stability of viability and immunizing potency of lyophilized, modified equine arteritis live-virus vaccine.},
  author={T O Harry and William H. McCollum},
  journal={American journal of veterinary research},
  year={1981},
  volume={42 9},
  pages={1501-5}
}
The Bucyrus strain of equine arteritis virus, previously modified to avirulence and vaccinal virus by 131 serial passages in primary cell cultures of horse kidney followed by 111 passages in primary cell cultures of rabbit kidney, was further passaged in cultures of the E. Derm (NBL-6) cell line, a continuous diploid cell line. Pools of the 16th and 25th passages of the virus in this last equine dermal cell line were lyophilized and stored in lots at 37 C, 23 to 28 C, 4C, and -20 C. The… CONTINUE READING