• Corpus ID: 219177522

Stability of gene regulatory networks

  title={Stability of gene regulatory networks},
  author={Yipei Guo and Ariel Amir},
  journal={arXiv: Biological Physics},
Homeostasis of protein concentrations in cells is crucial for their proper functioning, and this requires concentrations (at their steady-state levels) to be stable to fluctuations. Since gene expression is regulated by proteins such as transcription factors (TFs), the full set of proteins within the cell constitutes a large system of interacting components. Here, we explore factors affecting the stability of this system by coupling the dynamics of mRNAs and protein concentrations in a growing… 

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