Stability of coagulation factors in plasma prepared after a 24-hour room temperature hold.

@article{Alhumaidan2010StabilityOC,
  title={Stability of coagulation factors in plasma prepared after a 24-hour room temperature hold.},
  author={Hiba S Alhumaidan and Tracey A Cheves and Stein Holme and Joseph D Sweeney},
  journal={Transfusion},
  year={2010},
  volume={50 9},
  pages={1934-42}
}
BACKGROUND The manufacture of fresh-frozen plasma (FFP) requires that plasma be frozen within 8 hours of collection and 24-hour frozen plasma requires 1 to 6°C refrigeration before freezing. Manufacture of plasma after a room temperature hold for 24 hours, while convenient, could compromise clotting factor levels. STUDY DESIGN AND METHODS Pairs of FFP and 24-hour room temperature-frozen plasma (PLT-rich plasma [PRP]-24HRTFP) were manufactured from PRP after a room temperature hold for 8 and… CONTINUE READING

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