Stability of cimetidine hydrochloride in admixtures after microwave thawing.

@article{Elliott1983StabilityOC,
  title={Stability of cimetidine hydrochloride in admixtures after microwave thawing.},
  author={Gary T. Elliott and Malcolm McKenzie and Sarah Curry and John A. Pieper and Susan LeMessurier Quinn},
  journal={American journal of hospital pharmacy},
  year={1983},
  volume={40 6},
  pages={
          1002-6
        }
}
The stability of cimetidine hydrochloride in admixtures subjected to freezing and subsequent microwave thawing was studied. Admixtures containing cimetidine 300 mg were prepared using 18 50-ml bags of 5% dextrose injection and 18 100-ml bags of 0.9% sodium chloride injection. A sample for analysis of pH and drug concentration was withdrawn from each bag, and all admixtures were frozen for 28 days. Nine admixtures of each solution were thawed at room temperature and the other nine in a microwave… CONTINUE READING