Stability of angiogenic agents, ginsenoside Rg1 and Re, isolated from Panax ginseng: in vitro and in vivo studies.

@article{Yu2007StabilityOA,
  title={Stability of angiogenic agents, ginsenoside Rg1 and Re, isolated from Panax ginseng: in vitro and in vivo studies.},
  author={Lin-Chien Yu and S Chen and Wei-Chun Chang and Ya-Chun Huang and Kurt Ming-Chao Lin and Po-Hong Lai and H. -I. Sung},
  journal={International journal of pharmaceutics},
  year={2007},
  volume={328 2},
  pages={168-76}
}
The study was designed to investigate the stability of ginsenoside Rg(1) (Rg(1)) and Re (Re), two natural herbal compounds isolated from Panax ginseng, based on their activity to promote angiogenesis in vitro and in vivo. After being treated at different temperatures, pHs, and solvent species for distinct durations, the remaining activities of Rg(1) and Re on human umbilical vein endothelial cell (HUVEC) proliferation, migration, and tube formation were examined in vitro. Additionally, the… CONTINUE READING
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