Corpus ID: 67760472

Stability indicating spectrophotometric and TLC densitometric methods for the determination of gemifloxacin mesylate in tablet form

@article{Moussa2013StabilityIS,
  title={Stability indicating spectrophotometric and TLC densitometric methods for the determination of gemifloxacin mesylate in tablet form},
  author={B. Moussa and M. A. Mahrouse and M. Hassan and Michael Gamal Fawzy},
  journal={Analytical chemistry, an Indian journal},
  year={2013},
  volume={12}
}

B. Moussa, M. A. Mahrouse, +1 author Michael Gamal Fawzy

Published 2013

Chemistry

Analytical chemistry, an Indian journal

Gemifloxacin mesylate (GEM), a novel fluoroquinolone used for respiratory tract infections, was determined by three simple, accurate and precise spectrophotometric methods and a TLC densitometric method, in presence of its acid degradation product.Method (A) was first derivative technique (1D) which allows the determination of GEMbymeasuring the peak amplitudes at 280 and 360 nmwhere the acid degradation product displays zero value. Method (B) was based on second derivative ratio technique (2DD… CONTINUE READING

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