Stability indicating LC method for the simultaneous determination of amlodipine and olmesartan in dosage form.

@article{Patil2010StabilityIL,
  title={Stability indicating LC method for the simultaneous determination of amlodipine and olmesartan in dosage form.},
  author={Kashinath Rangu Patil and Vipul P Rane and Jaiprakash N. Sangshetti and Rajendra D. Yeole and Devanand Shinde},
  journal={Journal of chromatographic science},
  year={2010},
  volume={48 7},
  pages={601-6}
}
A simple, rapid, and precise method is developed for the quantitative simultaneous estimation of amlodipine (AM) and olmesartan (OL) in combined pharmaceutical dosage form. A chromatographic separation of the two drugs was achieved with an ACE 5 C(18) 25-cm analytical column using buffer-acetonitrile (60:40, v/v). The resolution between OL and AM was found to be more than 12. Theoretical plates for OL and AM were 6970 and 11,841, respectively. Tailing factor for OL and AM was 0.90 and 0.98… CONTINUE READING

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