Stability in symptoms of anxiety and depression as a function of genotype and environment: a longitudinal twin study from ages 3 to 63 years

@article{Nivard2014StabilityIS,
  title={Stability in symptoms of anxiety and depression as a function of genotype and environment: a longitudinal twin study from ages 3 to 63 years},
  author={Michel G. Nivard and Conor V. Dolan and Kenneth S. Kendler and Kees-Jan Kan and Gonneke Willemsen and Catharina E M van Beijsterveldt and Ram{\'o}n J. L. Lindauer and Jenny H. D. A. van Beek and Lot M. Geels and Meike Bartels and Christel M. Middeldorp and Dorret I. Boomsma},
  journal={Psychological Medicine},
  year={2014},
  volume={45},
  pages={1039 - 1049}
}
Background. The influence of genetic factors on major depressive disorder is lower than on other psychiatric disorders. Heritability estimates mainly derive from cross-sectional studies, and knowledge on the longitudinal aetiology of symptoms of anxiety and depression (SxAnxDep) across the lifespan is limited. We aimed to assess phenotypic, genetic and environmental stability in SxAnxDep between ages 3 and 63 years. Method. We used a cohort-sequential design combining data from 49 524 twins… 

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...

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