Stability, cutaneous delivery, and antioxidant potential of a lipoic acid and α-tocopherol codrug incorporated in microemulsions.

Abstract

The aim of this study was to assess the skin penetration, stability, and antioxidant effects of a α-tocopherol-lipoic acid codrug. To enhance penetration, we evaluated three microemulsions varying in water content and composition of the oil phase (isopropyl myristate with either monocaprylin or oleic acid). The codrug was incorporated at 1% (w/w). Codrug… (More)
DOI: 10.1002/jps.24053

Topics

6 Figures and Tables

Cite this paper

@article{Thomas2014StabilityCD, title={Stability, cutaneous delivery, and antioxidant potential of a lipoic acid and α-tocopherol codrug incorporated in microemulsions.}, author={Siji Thomas and Camila S. Vieira and Martha A. Hass and Luciana Biagini Lopes}, journal={Journal of pharmaceutical sciences}, year={2014}, volume={103 8}, pages={2530-8} }