Stability, blood partition, and protein binding of a chemoprotective agent, 2-(allylthio)pyrazine.

Abstract

The stability of 2-AP, a chemoprotective agent, in various pH solutions and human gastric juice, the blood partition of 2-AP between plasma and blood cells, and the factors influencing the binding of 2-AP to 4% human serum albumin (HSA) were evaluated. 2-AP was stable in human gastric juice and pH solutions ranging from 1 to 12, however, 2-AP was unstable… (More)

Topics

Cite this paper

@article{Han1998StabilityBP, title={Stability, blood partition, and protein binding of a chemoprotective agent, 2-(allylthio)pyrazine.}, author={K Han and Soo Ji Woo and Chang Hui Koo and M G Lee}, journal={Research communications in molecular pathology and pharmacology}, year={1998}, volume={101 2}, pages={171-8} }