Stability and potency of the Plasmodium falciparum MSP1-19/AMA-1(III) chimeric vaccine candidate with Montanide ISA720 adjuvant.

@article{Xue2010StabilityAP,
  title={Stability and potency of the Plasmodium falciparum MSP1-19/AMA-1(III) chimeric vaccine candidate with Montanide ISA720 adjuvant.},
  author={Xiangyang Xue and Feng Ding and Qingfeng Zhang and Xuegong Pan and Li Qu and Weiqing Pan},
  journal={Vaccine},
  year={2010},
  volume={28 18},
  pages={3152-8}
}
The Plasmodium falciparum AMA-1(III) and MSP1-19 proteins have been expressed as a chimera (PfCP-2.9), adjuvanted with Montanide ISA720 and developed as a vaccine candidate tested in human. The PfCP-2.9 protein contains 18 cysteine residues that form nine intramolecular disulfide bonds. The protective immune responses induced by the chimeric protein were… CONTINUE READING