Stability and activity of an Enterobacter aerogenes-specific bacteriophage under simulated gastro-intestinal conditions

@article{Verth2004StabilityAA,
  title={Stability and activity of an Enterobacter aerogenes-specific bacteriophage under simulated gastro-intestinal conditions},
  author={Kristof Verth{\'e} and Sam Possemiers and Niels Boon and Mario Vaneechoutte and Willy Verstraete},
  journal={Applied Microbiology and Biotechnology},
  year={2004},
  volume={65},
  pages={465-472}
}
A bacteriophage, designated UZ1 and showing lytic activity against a clinically important strain (BE1) of Enterobacter aerogenes was isolated from hospital sewage. The stability and lytic activity against this strain under simulated gastro-intestinal conditions was evaluated. After addition of bacteriophage UZ1 to a liquid feed at gastric pH 2, the phage was immediately inactivated and could not be recovered. However, by use of an antacid to neutralize stomach acidity, no significant changes in… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 45 references

Development of a six-stage culture system for simulating the gastrointestinal microbiota of weaned infants

P De Boever, R Wouters, V Vermeirssen, N Boon, W Verstraete
Microb Ecol Health Dis • 2001
View 4 Excerpts
Highly Influenced

Development of a 5-step multi-chamber reactor as a simulation of the human intestinal microbial ecosystem

K Molly, M Vande Woestijne, W Verstraete
Appl Microbiol Biotechnol • 1993
View 4 Excerpts
Highly Influenced

A conserved genetic module that encodes the major virion components in both the coliphage T4 and the marine cyanophage S-PM2.

Proceedings of the National Academy of Sciences of the United States of America • 2001
View 1 Excerpt

Bacteriophage therapy.

Antimicrobial agents and chemotherapy • 2001
View 3 Excerpts

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