Stability Analysis of Cell Dynamics in Leukemia

  title={Stability Analysis of Cell Dynamics in Leukemia},
  author={Hitay {\"O}zbay and Catherine Bonnet and Hinde Benjelloun and Jean Clairambault},
In order to better understand the dynamics of acute leukemia, and in particular to find theoretical conditions for the efficient delivery of drugs in acute myeloblastic leukemia, we investigate stability of a system modeling its cell dynamics. The overall system is a cascade connection of sub-systems consisting of distributed delays and static nonlinear feedbacks. Earlier results on local asymptotic stability are improved by the analysis of the linearized system around the positive equilibrium… CONTINUE READING
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