StAR-related lipid transfer (START) proteins: mediators of intracellular lipid metabolism.

@article{Soccio2003StARrelatedLT,
  title={StAR-related lipid transfer (START) proteins: mediators of intracellular lipid metabolism.},
  author={Raymond E Soccio and Jan L. Breslow},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 25},
  pages={
          22183-6
        }
}
StAR-related lipid transfer (START) domains are 210-amino acid lipid binding domains implicated in intracellular lipid transport, lipid metabolism, and cell signaling events. The prototype is the steroidogenic acute regulatory protein (StAR), which transfers cholesterol to mitochondria in steroid hormone-producing cells (1). START domains are found in an extensive protein family, including START domain only and multidomain proteins, but lipid ligands have only been identified in a few cases (2… CONTINUE READING

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