St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties

  title={St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties},
  author={J. Barnes and L. A. Anderson and J. Phillipson},
  journal={Journal of Pharmacy and Pharmacology},
The chemical composition of St. John's wort has been well‐studied. Documented pharmacological activities, including antidepressant, antiviral, and antibacterial effects, provide supporting evidence for several of the traditional uses stated for St John's wort. Many pharmacological activities appear to be attributable to hypericin and to the flavonoid constituents; hypericin is also reported to be responsible for the photosensitive reactions that have been documented for St. John's wort. With… Expand
586 Citations
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