Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast.

@article{Ganem2003Ssu72IA,
  title={Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast.},
  author={Carine Ganem and Fr{\'e}d{\'e}ric Devaux and Claire Torchet and Claude Jacq and Sophie Quevillon-Ch{\'e}ruel and Gilles Labesse and C{\'e}line Facca and G{\'e}rard Faye},
  journal={The EMBO journal},
  year={2003},
  volume={22 7},
  pages={1588-98}
}
Ssu72 is an essential yeast protein that is involved in transcription. It physically interacts with transcription initiation and termination complexes. In this report, we provide evidence that Ssu72 is a phosphatase that physically interacts with the CTD kinase Kin28 and functionally interacts with the CTD phosphatase Fcp1. A genome-wide expression analysis of mutant ssu72-ts69 during growth in complete medium revealed a number of defects, including the accumulation of a limited number of mRNAs… CONTINUE READING

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