SseJ deacylase activity by Salmonella enterica serovar Typhimurium promotes virulence in mice.

@article{Ohlson2005SseJDA,
  title={SseJ deacylase activity by Salmonella enterica serovar Typhimurium promotes virulence in mice.},
  author={Maikke B. Ohlson and Kerry Fluhr and Cheryl L. Birmingham and John H Brumell and Samuel I. Miller},
  journal={Infection and immunity},
  year={2005},
  volume={73 10},
  pages={6249-59}
}
Salmonella enterica serovar Typhimurium utilizes a type III secretion system (TTSS) encoded on Salmonella pathogenicity island-2 (SPI2) to promote intracellular replication during infection, but little is known about the molecular function of SPI2-translocated effectors and how they contribute to this process. SseJ is a SPI2 TTSS effector protein that is homologous to enzymes called glycerophospholipid-cholesterol acyltransferases and, following translocation, localizes to the Salmonella… CONTINUE READING

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