Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis.

@article{Djagaeva2005Src64II,
  title={Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis.},
  author={Inna Djagaeva and Sergey Doronkin and Steven K. Beckendorf},
  journal={Developmental biology},
  year={2005},
  volume={284 1},
  pages={143-56}
}
Src family tyrosine kinases respond to a variety of signals by regulating the organization of the actin cytoskeleton. Here, we show that during early oogenesis Src64 mutations lead to uneven accumulation of cortical actin, defects in fusome formation, mislocalization of septins, defective transport of Orb protein into the oocyte, and possible defects in cell division. Similar mutant phenotypes suggest that Src64, the Tec29 tyrosine kinase, and the actin crosslinking protein Kelch act together… CONTINUE READING

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