Src-mediated caveolin-1 phosphorylation affects the targeting of active Src to specific membrane sites

Src interactions with the plasma membrane are an important determinant of its activity. In turn, Src activity modulates its association with the membrane through binding of activated Src to phosphotyrosylated proteins. Caveolin-1 (Cav-1), a major component of caveolae, is a known Src phosphorylation target, and both were reported to regulate cell… CONTINUE READING

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