Src interacts with dynamin and synapsin in neuronal cells.

  title={Src interacts with dynamin and synapsin in neuronal cells.},
  author={Audrey Foster-Barber and J. Michael Bishop},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={95 8},
The nonreceptor tyrosine kinase Src is expressed at a high level in cells that are specialized for regulated secretion, such as the neuron, and is concentrated on secretory vesicles or at the site of exocytosis. To investigate the possibility that Src may play a role in regulating membrane traffic, we searched for neuronal proteins that will interact with Src. The SH3 domain of Src, but not that of the splice variant N-Src, bound to three proteins from mouse synaptosomes or PC12 cells: dynamin… CONTINUE READING


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Foster-Barber and Bishop Proc

  • R. Ren, B. J. Mayer, P. Cicchetti, Baltimore, D. Science 259, 1157–1161. Neurobiology
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