Src family kinases in tumor progression and metastasis

@article{Summy2004SrcFK,
  title={Src family kinases in tumor progression and metastasis},
  author={Justin M. Summy and Gary E. Gallick},
  journal={Cancer and Metastasis Reviews},
  year={2004},
  volume={22},
  pages={337-358}
}
The Src family of non-receptor protein tyrosine kinases plays critical roles in a variety of cellular signal transduction pathways, regulating such diverse processes as cell division, motility, adhesion, angiogenesis, and survival. Constitutively activated variants of Src family kinases, including the viral oncoproteins v-Src and v-Yes, are capable of inducing malignant transformation of a variety of cell types. Src family kinases, most notably although not exclusively c-Src, are frequently… Expand
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