Src-Tyrosine kinases are major agents in mitochondrial tyrosine phosphorylation.

  title={Src-Tyrosine kinases are major agents in mitochondrial tyrosine phosphorylation.},
  author={Elena Tibaldi and Anna Maria Brunati and Maria Lina Massimino and Annarita Stringaro and Marisa Colone and Enzo Agostinelli and Giuseppe Arancia and Antonio Toninello},
  journal={Journal of cellular biochemistry},
  volume={104 3},
Mitochondrial tyrosine phosphorylation is emerging as an important mechanism in regulating mitochondrial function. This article, aimed at identifying which kinases are the major agents in mitochondrial tyrosine phosphorylation, shows that this role should be attributed to Src family members. Indeed, various members of this family, for example, Fgr, Fyn, Lyn, c-Src, are constitutively present in the internal structure of mitochondria as well as Csk, a key enzyme in the regulation of the activity… CONTINUE READING

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