Sr-substituted hydroxyapatites for osteoporotic bone replacement.

  title={Sr-substituted hydroxyapatites for osteoporotic bone replacement.},
  author={E. Landi and Anna Tampieri and Giancarlo Celotti and Simone Sprio and Monica Sandri and Giandomenico Logroscino},
  journal={Acta biomaterialia},
  volume={3 6},
Porous apatites, which during resorption can release in situ Sr ions, were prepared to associate an anti-osteoporotic action with the peculiar features of the inorganic phase constituting the bone. Sr-substituted hydroxyapatite (SrHA) powder was directly synthesized using the classical neutralization route, but including Sr ions, and characterized. The higher solubility of SrHA granules of 400-600 microm size, potentially usable as a bone filler, was assessed compared with that of analogous… CONTINUE READING