Squid major lens polypeptides are homologous to glutathione S-transferases subunits

@article{Tomarev1988SquidML,
  title={Squid major lens polypeptides are homologous to glutathione S-transferases subunits},
  author={S. I. Tomarev and R. Zinovieva},
  journal={Nature},
  year={1988},
  volume={336},
  pages={86-88}
}
The eye lenses of cephalopods and vertebrates evolved relatively recently and by independent routes1. They provide a good experimental model for the study of convergent evolution at the protein level. One proposal is that pre-existing proteins were recruited as structural eye lens proteins during evolution2. This has been confirmed for the vertebrate eye lens structural proteins, or crystal-lins3–9, which have been intensively studied10,11. Despite the limited information about cephalopod eye… Expand
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The data indicate that the S-crystallins consist of a family of enzymatically inactive proteins which is considerably larger than previously believed and that GST activity was lost by gradual drift in sequence as well as by insertion of an extra peptide by exon shuffling. Expand
Lens Crystallins of Invertebrates
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The presence of overlapping AP-1 and antioxidant responsive-like sequences that appear functional in transfected vertebrate cells suggests that borrowing multifunctional proteins for refraction by a gene sharing strategy may have occurred in invertebrates as it did in vertebrates. Expand
Gene Families Coding for the Eye Lens Proteins of Cephalopods
TLDR
Characteristics of the major polypeptides of the squid and octopus lenses, obtained by cDNA cloning and sequencing are dealt with. Expand
O-Crystallin, arginine kinase and ferritin from the octopus lens.
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Three proteins have been identified in the eye lens of the octopus, Octopus dofleini, and one is called O-crystallin on the basis of its abundance in the transparent lens, while northern blots showed that ferritin mRNA is not lens-specific. Expand
Gene Sharing, Lens Crystallins and Speculations on an Eye/Ear Evolutionary Relationship1
  • J. Piatigorsky
  • Biology, Medicine
  • Integrative and comparative biology
  • 2003
TLDR
It is speculated on the basis of the current studies on Tripedalia that eyes and statocysts (associated with mechanoreceptors in many cnidarians and thus possibly ears in vertebrates) are evolutionarily related. Expand
Primary structure and lens-specific expression of genes for an intermediate filament protein and a β-tubulin in cephalopods
TLDR
SDS-PAGE and peptide sequencing indicated that the order of abundance of the cephalopod lens cytoskeletal proteins was IF proteins, actin and tubulins, consistent with an evolutionary relationship between IF proteins and lamins. Expand
J3-crystallin of the jellyfish lens: Similarity to saposins
TLDR
A crystallin role for the multifunctional saposin protein family in the jellyfish lens is suggested, extending the gene sharing evolutionary strategy for lens crystallins to the cnidarians and indicates that the putative primordial saposIn/swaposin J3-crystallin reflects both the chaperone and enzyme connections of the vertebrate crystallins. Expand
Lens proteins and their genes.
TLDR
It appears that at least, one of the typical structural proteins of the vertebrate lens—αB-crystallin—is by no means lens-specific, and research community is beginning to understand the way genes are expressed and regulated in the eye lens. Expand
Omega -crystallin of the scallop lens. A dimeric aldehyde dehydrogenase class 1/2 enzyme-crystallin.
TLDR
ALDH is the most diverse lens enzyme-crystallin identified so far, having been used as a lens crystallin in at least two classes of molluscs as well as elephant shrews. Expand
Evolution of Mollusc Lens Crystallins: Glutathione S-transferase/S-crystallins and Aldehyde Dehydrogenase/Ω-crystallins*
TLDR
Diverse crystallins (abundant water-soluble proteins) are responsible for the optical properties of transparent cellular eye lenses and are multifunctional proteins that have been recruited from stress proteins and enzymes by enhanced lens expression by convergent recruitment of the non-homologous crystallin genes. Expand
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References

SHOWING 1-10 OF 27 REFERENCES
Recruitment of enzymes as lens structural proteins.
TLDR
It now appears that the major taxon-specific crystallins of vertebrates and invertebrates are either enzymes or closely related to enzymes. Expand
Myxococcus xanthus spore coat protein S may have a similar structure to vertebrate lens βγ-crystallins
TLDR
It is shown that protein S has a striking homology with the β- and γ-crystallins of the vertebrate eye lens which are β-sheet proteins with internally duplicated structures, which implies that theβ- andγ- Crystallins evolved from already existing proteins, whose ancestors occurred in the prokaryotes. Expand
Physicochemical characterization of lens proteins of the squid Nototodarus gouldi and comparison with vertebrate crystallins.
The main water-soluble proteins of squid lens (S-crystallins) have a molecular weight of 60 000, a sedimentation coefficient s020,w of 5.2 S, 20-30% alpha-helical secondary structure, and anExpand
The enzyme lactate dehydrogenase as a structural protein in avian and crocodilian lenses
TLDR
It appears that an active enzyme has been recruited, unchanged, to an extra role as a structural protein in the lens without gene duplication and sequence divergence, which raises the possibility that other crystallins may similarly be enzymes expressed at high levels in lens as structural proteins. Expand
Characterization of lens crystallins and their mRNA from the carp lenses.
TLDR
Comparison of the amino acid compositions of carp gamma-Crystallin with those of bovine gamma-II, haddock gamma- and squid crystallins indicates that gamma-crystallin from the carp is very closely related to that of theHaddock, and probably also related to the invertebrate squid crystallin. Expand
Physicochemical characterization of a crystallin from the squid lens and its comparison with vertebrate lens crystallins.
  • S. Chiou
  • Chemistry, Medicine
  • Journal of biochemistry
  • 1984
TLDR
Biochemical comparison of the squid crystallin with mammalian lens crystallins shows that it is a crystallin distinguishable from all reported vertebrate lens crystall Ins, and a detailed study of this protein may shed light on the evolution of Lens crystallins in general. Expand
Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin.
  • T. D. Ingolia, E. Craig
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1982
TLDR
Comparison of the predicted sequence with the known sequences of other proteins revealed a remarkable similarity between this region of homology and the corresponding region of mammalian alpha-crystallin. Expand
The basic glutathione S-transferases from human livers are products of separate genes.
TLDR
The results indicate that the multiple basic human liver glutathione S-transferases are products of separate genes, and the proposal that deamidation may be a physiologically important process for generating glutathion S- transferases isozyme multiplicity can be all but ruled out. Expand
Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA.
  • C. Tu, B. Qian
  • Biology, Medicine
  • Biochemical and biophysical research communications
  • 1986
TLDR
The nucleotide sequence of the Ha subunit 1 cDNA, pGTH1, indicates that they are approximately 80% identical base-for-base without any deletion or insertion, and comparison of amino-acid replacement mutations in these coding sequences revealed that the percentage divergence between the rat Ya and Yc genes is more than that between the Ha and Ya or Ha and YC genes. Expand
Gene sharing by delta-crystallin and argininosuccinate lyase.
TLDR
The data indicate that the same gene, at least in ducks, encodes two different functions, an enzyme (ASL) and a structural protein (delta-crystallin), although in chickens specialization and separation of functions may have occurred. Expand
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