Squamous cell carcinoma of the oropharynx

@article{Parsons2002SquamousCC,
  title={Squamous cell carcinoma of the oropharynx},
  author={James T. Parsons and William M. Mendenhall and Scott P. Stringer and Robert J. Amdur and Russell W. Hinerman and Douglas Villaret and Giselle J Moore-Higgs and Bruce D. Greene and Tod W. Speer and Nicholas J. Cassisi and Rodney R. Million},
  journal={Cancer},
  year={2002},
  volume={94}
}
The treatment of patients with squamous cell carcinoma (SCC) of the oropharynx remains controversial. No randomized trial has addressed adequately the question of whether surgery (S), radiation therapy (RT), or combined treatment is most effective. 

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...

References

SHOWING 1-10 OF 112 REFERENCES

Surgical treatment of squamous cell carcinoma of the base of tongue

The experience with primary surgery followed by postoperative radiation therapy (XRT) to determine the impact of the treatment protocols on outcome was reviewed.

Definitive radiotherapy for T1 and T2 squamous cell carcinoma of the tonsil

To assess whether survival or local control of early squamous cell carcinoma of the tonsil has been compromised by a moderate‐dose approach, a large number of patients diagnosed with this disease have had their tonsil removed.

Carcinoma of the tonsillar region

A retrospective analysis of 171 patients with carcinoma of the tonsillar region is presented, finding the presence of nodal disease decreased survival by one half.

Radiation therapy of carcinoma of the tonsil

The results of treatment with radiation therapy of 65 cases of epidermoid carcinoma of the palatine tonsil have been reviewed and no difference in survival was noted between patients with no clinical adenopathy vs those with clinically involved movable ipsilateralAdenopathy.

Excellent functional outcome in patients with squamous cell carcinoma of the base of tongue treated with external irradiation and interstitial iodine 125 boost

Local control, functional outcome, and complications in patients with carcinoma of the base of tongue (BOT) were analyzed to assess the impact of interstitial implant boost with I‐125 seeds.

Combined surgery and postoperative radiotherapy for carcinoma of the base of tongue: Analysis of treatment outcome and prognostic value of margin status

It is the institutional policy to manage base of tongue carcinoma with combined partial glossectomy (with attempt to avoid laryngectomy if possible) with planned postoperative radiotherapy (RT), and it is reported on the institutional experience with this approach.

Tonsil cancer. Patterns of failure after surgery alone and surgery combined with postoperative radiation therapy

Background. The authors determined the patterns of treatment failure in patients treated with surgery alone or surgery combined with postoperative radiation therapy for squamous cell carcinoma of the

Local control of oropharyngeal carcinoma by irradiation alone

The accelerated hyperfractionated radiation therapy twice‐daily program was shown to achieve significantly higher 5‐year local tumor control rates and disease‐specific survival rates than the conventional once‐daily radiation therapy program (historical control).
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