Squamous cell carcinoma of the oral mucosa after release of submucous fibrosis and bilateral small radial forearm flap reconstruction.

@article{Celik2002SquamousCC,
  title={Squamous cell carcinoma of the oral mucosa after release of submucous fibrosis and bilateral small radial forearm flap reconstruction.},
  author={Naci Celik and Fu-chan Wei and Yang-Ming Chang and Wen-guei Yang and Da-jeng Chen and Chi-Ying Tsai},
  journal={Plastic and reconstructive surgery},
  year={2002},
  volume={110 1},
  pages={34-8}
}
Oral submucous fibrosis is a collagen disorder that affects the submucosal layer of the upper digestive tract. The major cause is the habit of betel quid chewing, which is common in central, southern, and southeast Asia. The progressive and irreversible course of disease results with trismus, dysphagia, xerostomia, and rhinolalia. The most serious complication of this disorder is the development of oral carcinoma, and the incidence in different series varies from 1.9 to 10 percent. A sufficient… CONTINUE READING