Squamous cell carcinoma of the bladder: pathology, diagnosis and treatment

  title={Squamous cell carcinoma of the bladder: pathology, diagnosis and treatment},
  author={Ahmed A. Shokeir},
  journal={BJU International},
  • A. Shokeir
  • Published 1 January 2004
  • Medicine
  • BJU International
Squamous cell carcinoma (SCC) can occur in both nonbilharzial and bilharzial bladders; the two subtypes differ in epidemiology, pathogenesis and clinicopathological features. The nonbilharzial type occurs in Western countries and represents < 5% of all vesical tumours; it occurs most often in the seventh decade with a slight male predominance. The principal predisposing factor is prolonged indwelling urethral catheterization in patients with spinal cord injury and the main symptom is haematuria… 
Squamous Cell Carcinoma of the Bladder Mimicking Interstitial Cystitis and Voiding Dysfunction
A 39-year-old Caucasian female presented with bladder and lower abdominal pain, urinary frequency, and nocturia which was originally believed to be interstitial cystitis but was later diagnosed as SCC of the bladder, which is a relatively uncommon cause of bladder cancer.
Other Types of Carcinoma
Urachal adenocarcinoma is usually discussed together with bladder adenOCarcinomas, because they share many clinical and histological features.
From the Archives of the AFIP: neoplasms of the urinary bladder: radiologic-pathologic correlation.
In the United States, primary bladder neoplasms account for 2%-6% of all tumors, with bladder cancer ranked as the fourth most common malignancy. Ninety-five percent of bladder neoplasms arise from
Squamous Cell Carcinoma of the Bladder: A Clinicopathologic Analysis of 45 Cases
In conclusion, squamous cell carcinoma often presents at an advanced stage; however, radical cystectomy with lymph node dissection appears to offer a significant benefit in survival in a subset of patients.
Nonbilharzial squamous cell carcinoma and transitional cell carcinoma with squamous differentiation of the lower and upper urinary tract
SCC is characterized by poor prognosis and individual tumor biology, indicating the necessity of an early radical surgery, and the role of adjuvant therapy on SCC and TCC/SCC further trials are needed.
Do pure squamous cell carcinomas and urothelial carcinomas have similar prognosis after radical cystectomy?
Although pure SCC cases are diagnosed at advanced stages of the disease, UC and pure S CC cases have similar prognosis by stages, and lymph node involvement and stages are the most important prognostic factors after radical cystectomy.
Non‐urothelial carcinomas of the bladder
This paper will review non‐urothelial carcinomas in each of these three morphological categories, emphasising recent changes in diagnostic grouping and challenges in the histopathological diagnosis, and discuss well‐differentiated neuroendocrine neoplasms of the bladder.
Pathology outcomes in patients with transurethral bladder tumour resection in a Turkish population: A retrospective analysis.
  • S. Budak, C. Yücel, Z. Kozacioglu
  • Medicine
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
  • 2018
The incidence of bladder carcinoma varies between regions and increased smoking and exposure to environmental carcinogenetic agents may lead to altered incidences and histological types of bladder tumours.
Squamous Cell Carcinoma of the Urinary Bladder: Clinicopathological and Molecular Update
TERT promoter mutations, commonly found in conventional urothelial carcinoma, are also highly prevalent in urinary bladder squamous cell carcinoma suggesting a common tumorgenesis and potential utility as a molecular urine-based-screening assay.


Pure Squamous Cell Carcinoma of the Bladder in Western Countries
Introduction: Pure squamous carcinoma (SCC) is a rare entity in western regions. The management of SCC still remains similar to that of transitional carcinoma, although it is a different entity. A
[Squamous cell carcinoma of the urinary bladder. Clinico-pathologic study of 7 cases].
A retrospective review of 552 patients with primary bladder cancer yielded 7 cases of pure squamous cell carcinoma, all of them deeply invasive, which were large and frequently affected more than one topographic area.
[Epidermoid carcinoma of the bladder].
Squamous carcinoma of the bladder is a rare tumour, little known in Western countries in contrast with the high incidence in the Middle East and East Africa. It has a sex-ratio of 1 and black
[Epidermoid carcinoma of the bladder. Apropos of 14 cases].
The authors report 14 cases of squamous cell carcinoma of bladder over a period of 20 years, with a mean age of 56 years, of which 12 total cystoprostatectomies were performed and 2 patients were treated exclusively by radiotherapy.
Squamous cell carcinoma of bladder. A review of 114 patients.
No conclusions concerning the role of total cystectomy could be drawn from this series because of the small number of patients undergoing the operation, but a review of the literature suggests this may be the treatment of choice.
Carcinoma of the bilharzial urinary bladder.A study of the associated mucosal lesions in 86 cases
The mucosal lesions in the lower urinary tract were examined in 86 cystectomy specimens of bilharzial bladder cancer and it was found that squamous cell carcinoma and adenocarcinoma probably arise from metaplastic epithelium.