Squamous cell carcinoma cells differentially stimulate NK cell effector functions: the role of IL-18


Tumor cells stimulate natural killer (NK) cell effector functions, but the regulation of cytokine secretion and cytolysis is incompletely understood. We tested whether oral and pharyngeal squamous cell carcinoma cell lines differentially stimulated NK cell interferon-γ (IFN-γ) secretion and cytolysis using a clone of the NK-92-transformed human NK cell… (More)
DOI: 10.1007/s00262-002-0361-8


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