Corpus ID: 33027208

Sputum induction in corticosteroid-dependant asthmatics: risks and airway cellular profile.

  title={Sputum induction in corticosteroid-dependant asthmatics: risks and airway cellular profile.},
  author={L. Loh and V. Kanabar and M. D'Amato and N. Barnes and B. O'Connor},
  journal={Asian Pacific journal of allergy and immunology},
  volume={23 4},
  • L. Loh, V. Kanabar, +2 authors B. O'Connor
  • Published 2005
  • Medicine
  • Asian Pacific journal of allergy and immunology
  • Sputum induction with nebulized hypertonic saline is increasingly being used to evaluate airway inflammation. We investigated the procedure-associated risk in 16 asthmatics that were still symptomatic despite on high doses of regular corticosteroid (CS) therapy (7 on daily inhaled CS > or = 800 microg budesonide or equivalent; 9 on additional daily oral CS) and their sputum cellular profile. For comparison, 12 mild stable asthmatics and 10 normal healthy subjects were included. All subjects… CONTINUE READING
    10 Citations
    Cytoplasm-nuclear trafficking of CREB and CREB phosphorylation at Ser133 during therapy of chronic obstructive pulmonary disease.
    • R. Mróz, A. Hołownia, +5 authors W. MacNee
    • Medicine
    • Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
    • 2007
    • 21
    • PDF
    British Guideline on the Management of Asthma
    • 978
    • PDF


    Sputum in severe exacerbations of asthma: kinetics of inflammatory indices after prednisone treatment.
    • 281
    Neutrophilic inflammation in severe persistent asthma.
    • 831
    • PDF
    Assessment of airway inflammation in children with acute asthma using induced sputum.
    • 93
    • PDF
    Safety of inducing sputum in patients with asthma of varying severity.
    • 86
    Use of induced sputum cell counts to investigate airway inflammation in asthma.
    • 906
    • PDF