Sputum club cell protein concentration is associated with pulmonary exacerbation in cystic fibrosis.

@article{Laguna2015SputumCC,
  title={Sputum club cell protein concentration is associated with pulmonary exacerbation in cystic fibrosis.},
  author={Theresa A Laguna and Cynthia Williams and Kyle Robert Brandy and Cole Welchlin-Bradford and Catherine E. Moen and Cavan S. Reilly and Chris H Wendt},
  journal={Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society},
  year={2015},
  volume={14 3},
  pages={
          334-40
        }
}
BACKGROUND Cystic fibrosis (CF) patients exhibit a progressive decline in lung function accelerated by intermittent pulmonary exacerbations. There are urgent needs for clinically relevant biomarkers to aid in the diagnosis and management of a CF pulmonary exacerbation, in addition to providing insight into its pathophysiology. Club cell secretory protein (CCSP) is produced by bronchial epithelial cells, known to have anti-inflammatory properties and may play a role in CF pulmonary exacerbations… CONTINUE READING
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