Sprouty2 is involved in the control of osteoblast proliferation and differentiation through the FGF and BMP signaling pathways.

Abstract

Fibroblast growth factor (FGF) and bone morphogenetic protein (BMP) play essential roles in bone formation and osteoblast activity through the extracellular signal-regulated kinase 1/2 (ERK1/2) and Smad pathways. Sprouty family members are intracellular inhibitors of the FGF signaling pathway, and four orthologs of Sprouty have been identified in mammals… (More)
DOI: 10.1002/cbin.10876

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Cite this paper

@article{Taketomi2017Sprouty2II, title={Sprouty2 is involved in the control of osteoblast proliferation and differentiation through the FGF and BMP signaling pathways.}, author={Takaharu Taketomi and Tomohiro Onimura and Daigo Yoshiga and Daichi Muratsu and Terukazu Sanui and Takao Fukuda and Jingo Kusukawa and Seiji Nakamura}, journal={Cell biology international}, year={2017} }